Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice
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چکیده
منابع مشابه
Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice
Calorie restriction results in leanness, which is linked to metabolic conditions that favor longevity. We show here that deficiency of the triglyceride synthesis enzyme acyl CoA:diacylglycerol acyltransferase 1 (DGAT1), which promotes leanness, also extends longevity without limiting food intake. Female DGAT1-deficient mice were protected from age-related increases in body fat, tissue triglycer...
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ژورنال
عنوان ژورنال: Aging
سال: 2012
ISSN: 1945-4589
DOI: 10.18632/aging.100424